Noone can ever answer this question on the internet with any great amount of certainty, as its so dependant on soil conditions.
The soil in our garden is such that, to move it, you need a pickaxe very quickly, as its, basically, bonded rock.
Where my folks live, in essex, its clay, which expands and contracts with moisture.
My old man is a (retired) buildings surveyor, but he is useless for any information of that type for the soil that i have here - he could spec foundation depth required for the area where he worked, but its just not the same all over.
Regs are a bit of a blanket coverage, but youre not dealing with them for a shed... (and if you were, you would be hiring in skips for the amount of spoil you would need to remove).
All that said, 4" of concrete, over 2" of decent subbase does not sound bad, provding you have solid soil that's not going to move about too much with moisture content. For what it will cost you, put in some mesh also, but make sure its centralised, as it should be 50mm from ether face. You will probably need another inch in there though, if you want to blind the subbase, and put in a DPM at that point.