The positive aspects of this system, as I see them, is:-
Affordable
Relatively easy
Greater glue area in the joint
Longer/Deeper mortise and tenons possible
Negatives:-
Slower
Less adaptable
Difficult to produce your own tenons to suit (in a timber of your choice)
Longer set up time
Lack of easy repeatability
Tenon size fixed at 3/8" for 3/4" stock or greater (thinner stock i.e. drawer boxes ignored)
Beadlock tenons cost £34.75 per 100 @50mm length, Domino's cost for 10x50mm approx £13.00 per 100
While the cost of the Domino and let us not forget the need for dust extraction does seem high, the benefits for a professional in the woodworking field or a productive hobbiest are, frankly, impressive.
My Elu biscuit joiner was retired from the first moment I used a domino, but I do this for a living (albeit one I enjoy immensely :wink: )
Given the uses for the above advertised beadlock jig I think the Kreg screw based jig is a better option on a cost basis.
Rob.